Medical

For this meeting, I wanted to give everyone a break from all the data and analysis we’ve been doing lately and dive into something way more philosophical: biomedical ethics. We talked about how medicine isn’t just about science and how it’s about people, values, and decisions that sometimes don’t have a perfect answer. I started […]

For this meeting, I wanted to dive deep into something that doesn’t get enough attention when people read scientific papers: limitations. Everyone always talks about results and conclusions, but no one really teaches how to think critically about what a study can’t prove. I wanted our members to not just read research but to question

This is a scientific literature review on the article Muscle Stem Cell-Derived Extracellular Vesicles Reverse Hydrogen Peroxide-Induced Mitochondrial Dysfunction in Mouse Myotubes which you can find here https://pubmed.ncbi.nlm.nih.gov/33256005/ The experiment was a long one, so I decided to split the review up into two parts; that way, it won’t be such a long read. The

Introduction: A Revolutionary Step in Genetic Science For decades, scientists have dreamed of having the ability to modify genes with precision, to go into the very blueprint of life and make changes that could cure diseases, strengthen crops, and even potentially shape the evolution of living organisms. Yet, for most of history, genetic engineering was

In this post, I will be presenting my scientific literature review of the following article:  https://pmc.ncbi.nlm.nih.gov/articles/PMC11078688/ Article Reviewed:The Use of CRISPR-Cas9 Genetic Technology in Cardiovascular Disease: A Comprehensive Review of Current Progress and Future Prospective. Authors:Asif M, Khan WJ, Aslam S, Aslam A, Chowdhury MA. Introduction and Background This review outlines the transformative journey of

Article Reviewed:Terns MP, Terns RM. CRISPR-based adaptive immune systems. Curr Opin Microbiol. 2011 Jun;14(3):321-7. doi: 10.1016/j.mib.2011.03.005. Epub 2011 Apr 29. PMID: 21531607; PMCID: PMC3119747. Introduction to CRISPR-Cas Systems CRISPR-Cas systems represent one of the most remarkable discoveries in the study of prokaryotic immunity. These small RNA-guided systems provide adaptive and heritable defense against a variety

Article Reviewed:Kennedy EM, Kornepati AV, Goldstein M, Bogerd HP, Poling BC, Whisnant AW, Kastan MB, Cullen BR. Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease. J Virol. 2014 Oct;88(20):11965-72. doi: 10.1128/JVI.01879-14. Epub 2014 Aug 6. PMID: 25100830; PMCID: PMC4178730. Overview of CRISPR CRISPR

Introduction The CRISPR-Cas9 system represents a groundbreaking advance in gene editing and functional genomics, allowing scientists to target and modify specific genomic loci with precision. This method, which uses guide RNA (gRNA) sequences to direct Cas9 endonuclease activity, can induce double-strand breaks in DNA, which are then repaired by cellular mechanisms that often result in

Abstract: The experiment conducted in this research article explored the possibilities of using muscle stem cells to repair damaged and dysfunctional muscles. This type of therapy could be a form of treatment for people with muscular dystrophy. The disease that was focused on here was Duchenne muscular dystrophy (DMD). To understand the aim of this

General Idea This study investigates how social isolation affects brain function in mice, focusing on cognitive (thinking and memory) impairments. It also looks at how a substance called dihydromyricetin (DHM), found in some plants, could help reverse these effects. Mice that were socially isolated for some time developed poorer memory and cognitive performance. Changes occurred