Pre-Med Club

Genome-Scale Functional Genomics Using CRISPR-Cas9: Advancements, Challenges, and Applications in Identifying Essential Genes

Introduction The CRISPR-Cas9 system represents a groundbreaking advance in gene editing and functional genomics, allowing scientists to target and modify specific genomic loci with precision. This...

MuSC-EVs in Mice

Abstract: The experiment conducted in this research article explored the possibilities of using muscle stem cells to repair damaged and dysfunctional muscles. This type of therapy could be a form of...

Dihydromyricetin Improves Social Isolation‐Induced Cognitive Impairments and Astrocytic Changes in Mice

General Idea This study investigates how social isolation affects brain function in mice, focusing on cognitive (thinking and memory) impairments. It also looks at how a substance called...

Health Science Immersion Program (HSIP) Review

The HSIP program that I attended was also very valuable. The program gave me an unusual and broad exposure to the enormity and the diversity within medicine that I had not appreciated beforehand. It...

Summer at Hopkins Recap

Back in November 2023, when I was researching various summer programs, I came across the Summer at Hopkins program and I was immediately drawn to it.  Johns Hopkins had always been one of my...

CRISPR-Based Adaptive Immune Systems

The paper introduces CRISPR-Cas systems as small RNA-based defense systems that execute adaptive and heritable immunity against viruses, plasmids, and other mobile genetic elements in archaea and...

Genome-Scale CRISPR-Cas 9 Knockout Screening in Human Cells

Introduction The CRISPR-Cas9 system, which can be programmed to target specific genomic loci (position), offers a powerful tool for gene editing and functional genomics. This study demonstrates...

CRISPR – Cas

Overview of CRISPR CRISPR is a technology that enables researchers to edit parts of a genome. It works via the enzyme Cas9 and a guide RNA strand. Cas9 acts as a pair of ‘molecular scissors’ that can...